Welcome to Wang Lab!

We are in the Department of Genetics and Center for Genome Sciences & Systems Biology at Washington University in St. Louis, School of Medicine.

Phone: Ting's Office (Room 5211): (314) 286-0865
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Epigenetic therapy potentiates transposable element transcription to create tumor-enriched antigens in glioblastoma cells

Abstract: Inhibiting epigenetic modulators can transcriptionally reactivate transposable elements (TEs).…

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Regulatory transposable elements in theencyclopedia of DNA elements

Abstract: Transposable elements (TEs) comprise ~50% of our genome, but knowledge of how TEs affect genome…

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LINE1 mediates long-range DNA interactions

Abstract: The impact of transposable elements (TEs) on gene regulatory networks and how they are governed…

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Cis-regulatory evolution of the recently expanded Ly49 gene family

Abstract: Comparative genomics has revealed the rapid expansion of multiple gene families involved in…

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Towards targeting transposable elements for cancer therapy

Abstract: Transposable elements (TEs) represent almost half of the human genome. Historically deemed ‘junk…

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Using long-read CAGE sequencing to profile cryptic-promoter-derived transcripts and their contribution to the immunopeptidome

Abstract: Recent studies have shown that the noncoding genome can produce unannotated proteins as antigens…

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