4-6-2017. Hyung Joo, Yiran, and Josh's proposal "Identification of regulatory elements responsible for zebrafish regeneration" has been awarded $10,000 funding by the Children’s Discovery Institute’s Zebrafish Models for Pediatric Research Services Cooperative (ZRSC).
3-30-2017. Jing's paper is highlighed by EurekAlert for news release: Cancer cells disguise themselves by switching off genes, new research reveals.
3-28-2017. Vasavi's paper is online at Nature Communications now.
3-23-2017. Rebecca's paper is online at PLOS One now.
3-6-2017. Rebecca's paper "Epigenetic annotation of noncoding mutations identifies mutated pathways in primary liver cancer" has been accepted by PLOS One! Congratulations, Rebecca!!
2-2-2017. The Wang Lab received an U01 grant for Computational Analysis as part of NHGRI's extension of the ENCODE Project which catalogs genes and regulatory regions. [NIH news release]
1-12-2017. Jing's paper on uterine carcinosarcoma is online now at Neoplasia.
1-11-2017. Erika Schumacher joins the lab for a rotation. Welcome, Erika!
12-14-2016. Vasavi's paper "Functional cis regulatory modules encoded by mouse-specific endogenous retrovirus" has been accepted by Nature Communications! Congratulations, Vasavi!!
12-12-2016. Jing's paper on uterine carcinosarcoma has been accepted by Neoplasia! Congratulations, Jing!
11-17-2016. Ju Heon Maeng joins the lab for a rotation. Welcome, Ju Heon!
11-11-2016. Cheng Lyu joins the lab as a part time research assistant. Welcome, Cheng!
10-20-2016. Wang lab is going to host WashU Epigenome Day 2016 on Monday, November 21.
10-10-2016. Ananda Datta joins the lab as a postdoc. Welcome, Ananda!
9-16-2016. Rebecca Lowdon successfully defended her PhD thesis "The Epigenomics of Cell Fate in Development and Disease". Congratulations Dr. Lowdon! Some pictures.
8-22-2016. Jonathan Spalding joins the lab for a rotation. Welcome, Jonathan!
8-13-2016. 2nd lab float trip. Some pictures.
8-12-2016. "Inhibition of DNA Methyltransferases Blocks Mutant Huntingtin-Induced Neurotoxicity", a collaboration with Dr. Yano at Department of Neurological Surgery, Washington University School of Medicine, is online now at Scientific Reports. Xiaoyun and Ting are co-authors. Congratulations!
8-1-2016. Alan Du joins the lab for a rotation. Welcome, Alan!
7-31-2016. 7th annual summer party. Some pictures.
7-1-2016. We got a U24 grant to build the Environmental Epigenomics Data Coordination Center.
6-30-2016. Daniel Cui joins the lab for a rotation. Welcome, Daniel!
6-6-2016. Xiaoyu Zhuo joins the lab as a postdoc. Welcome, Xiaoyu!
6-6-2016. Abbie Bowman and Julia Altman join lab as summer students. Welcome, Abbie and Julia!
6-2-2016. Silas Hsu joins the lab as a summer Master student. Welcome, Silas!
5-27-2016. Justin Chen joins the lab again as a summer student. Welcome back, Justin!
5-17-2016. Vasavi Sundaram successfully defended her PhD thesis "Identifying the regulatory role of transposable elements in mammalian genomes". Congratulations Dr. Sundaram! Some pictures.
5-16-2016. David Zhang joins the lab again as a summer undergraduate student. Welcome back, David!
4-12-2016. Rebecca and Josh's review article is online at Trends in Genetics now.
4-4-2016. Juan Macias joins the lab for a rotation. Welcome, Juan!
3-22-2016. Yiran Hou joins the lab for her thesis study. Welcome, Yiran!
3-9-2016. Eileen Chen joins the lab as a summer medical student. Welcome, Eileen!
3-3-2016. Rebecca and Josh's review article "Evolution of epigenetic regulation in vertebrate genomes" has been accepted by Trends in Genetics! Congratulations, Rebecca and Josh!!
2-17-2016. Junchen's paper is online at G3 now.
2-3-2016. Junchen's paper "Mapping of variable DNA methylation across multiple cell types defines a dynamic regulatory landscape of the human genome" is accepted by G3. Congratulations, Junchen!
2-1-2016. Erica Pehrsson joins the lab for her postdoc training. Welcome Erica!
12-31-2015. Yiran Hou joins the lab for a rotation. Welcome Yiran!
12-4-2015. The Wang lab has moved to the new McKinley Scott Research Building! Some pictures.
11-30-2015. Aldrin Yim joins the lab for a rotation. Welcome Aldrin!
11-25-2015. The MGLL paper, a collaboration with Dr. Ryan Bogdan, is published in the Journal of Abnormal Psychology.
11-16-2015. Chengran Yang joins the lab for a rotation. Welcome Chengran!
10-27-2015. The paper "Perinatal deiodinase 2 expression in hepatocytes defines epigenetic susceptibility to liver steatosis and obesity" is online now at PNAS.
10-20-2015. WashU EpiGenome Browser workshop at The First International Epigenomics Conference in Fudan University, Shanghai, China. Workshop website.
9-29-2015. "Perinatal Deiodinase 2 Expression in Hepatocytes Defines Epigenetic Susceptibility to Liver Steatosis and Obesity", a collaboration with Dr. Bianco at Rush University Medical Center, has been accepted for publication at PNAS. Daofeng, Xiaoyun and Ting are co-authors. Congratulations!
9-25-2015. Nakul Shah joins the lab for research training. Welcome, Nakul!
9-16-2015. We have received a U01 grant from NCI to establish "THE WASHU 4DN NETWORK DATA COORDINATION AND INTEGRATION CENTER", with a focus on integration of genomic data and imaging data, grant announcement and press release.
9-3-2015. Mikayla Choi joins the lab to conduct undergraduate research. Welcome, Mikayla!
8-21-2015. Junchen Gu successfully defended his PhD thesis "Variation and Plasticity of DNA methylation in Genome Regulation". Congratulations Dr. Gu! Some pictures.
8-6-2015. Lab float trip at Meramec River. Some pictures and videos.
8-4-2015. Our collaboration with Professor Elliot C. Nelson at Department of Psychiatry "Evidence of CNIH3 involvement in opioid dependence" is online now at Molecular Psychiatry.
8-1-2015. 6th annual summer party. Some pictures.
7-9-2015. Jennifer Flynn joins the lab for her thesis study. Welcome back, Jennifer!
7-6-2015. Ivy Chen joins the lab as a summer intern. Welcome, Ivy!
7-1-2015. Ting is promoted to Associate professor with tenure! Cheers!!
6-22-2015. Asia M. Paguntalan, Tammy Ray and Justin Chen join lab as summer students. Welcome Asia, Tammy and Justin!
6-16-2015. Our collaboration with Professor Elliot C. Nelson at Department of Psychiatry, Wash U, on "Evidence of CNIH3 involvement in opioid dependence" has been accepted by Molecular Psychiatry. Bo, Ting and Xin are co-authors. Congratulations!
6-9-2015. Our collaboration with Dr. Ryan Bogdan at Department of Psychology, Wash U, on "Endocannabinoid variants and childhood adversity predict cannabis dependence symptoms and amygdala habituation" has been accepted by Journal of Abnormal Psychology. Bo, Daofeng and Ting are co-authors. Congratulations!
6-4-2015. Mayank Choudhary joins the lab for his thesis study. Welcome, Mayank!
6-1-2015. Diana Jiang joins the lab as a summer medical student. Welcome, Diana!
5-11-2015. David Zhang joins the lab as a summer undergraduate student. Welcome, David!
4-28-2015. Yu He joins the lab for his thesis study. Welcome, Yu!
4-24-2015. GiNell Elliott successfully defended her PhD thesis "Complex Genome Regulation Characterized by Atypical Signatures in DNA Methylation". Congratulations Dr. Elliott! Some pictures.
3-30-2015. Josh joins the lab for his thesis study. Welcome back, Josh!
3-25-3015. Our collaboration with Dr. Kyunghee Choi's group "Induction of hematopoietic and endothelial cell program orchestrated by ETS transcription factor ER71/ETV2" is online now at EMBO reports.
2-26-2015. Our collaboration with Dr. Kyunghee Choi's group at Department of Pathology and Immunology on "Induction of hematopoietic and endothelial cell program orchestrated by ETS transcription factor ER71/ETV2" has been accepted by EMBO Reports! Daofeng is the 2nd author, and Ting is co-corresponding author. Congratulations!!
2-23-2015. News release on Hyung Joo's paper: Epigenome orchestrates embryonic development.
2-20-2015. Hyung Joo's paper "Developmental enhancers revealed by extensive DNA methylome maps of zebrafish early embryos" in now online at Nature Communications!
2-18-2015. News release on our Roadmap papers: Scientists unveil map of human epigenomes in effort to fight disease.
2-18-2015. The Roadmap flagship paper is online at Nature: Integrative analysis of 111 reference human epigenomes. Daofeng, Rebecca, GiNell and Bo are Integrative analysis co-leads; Junchen, Nicole, Renee, Xiaoyun are Analysis and production contributors, and Ting is one of Co-principal investigators. Congratulations!!
2-18-2015. Xin's Roadmap EpiGenome Browser paper is online at Nature Biotechnology: Epigenomic annotation of genetic variants using the Roadmap Epigenome Browser.
2-18-2015. GiNell's paper "Intermediate DNA methylation is a conserved signature of genome regulation" is now online at Nature Communications!
2-16-2015. Nicholas Jacobs joins the lab for a rotation. Welcome Nicholas!
2-4-2015. Mayank Choudhary joins the lab for a rotation. Welcome Mayank!
1-26-2015. Jennifer Flynn joins the lab for a rotation. Welcome Jennifer!
1-23-2015. GiNell's paper "Intermediate DNA Methylation is a Conserved Signature of Genome Regulation" has been accepted by Nature Communications. Congratulations GiNell!
1-20-2015. Deepak Purushotham joins the lab as Research Analyst. Welcome Deepak!
1-19-2015. Hyung Joo's paper "Developmental enhancers revealed by extensive DNA methylome maps of zebrafish early embryos" has been accepted by Nature Communications. Congratulations Hyung Joo!
1-12-2015. Yu He joins the lab for a rotation. Welcome Yu!
1-5-2015. The Roadmap EpiGenome Browser paper has been accepted by Nature Biotechnology! Congratulations Xin!
11-25-2014. Rebecca's paper "Regulatory network decoded from epigenomes of surface ectoderm-derived cell types" is online today: here. This is the first Roadmap Consortium companion paper.
11-24-2014. Jia Zhou successfully defended her PhD thesis "Principles of epigenome evolution". Congratulations Dr. Zhou! Some pictures.
11-19-2014. News release on Vasavi's paper: Exploring the genomes of mice and men (New insight can help determine when mouse models are good stand-ins for studying humans).
11-19-2014. A Mouse ENCODE Consortium companion paper studying principles of regulatory information conservation between mouse and human is published in Nature. Vasavi, Xiaoyun and Ting are co-authors. Congratulations!!
11-19-2014. The main paper of Mouse ENCODE Consortium is published in Nature. Ting and Rebecca are co-authors. Congratulations!!
11-6-2014. Our MeDIP/MRE pipeline for investigating genome-wide CpG methylation is published in Methods.
10-24-2014. Nicole joins the lab for her thesis study. Welcome, Nicole!
10-19-2014. Workshop at 2014 ASHG: Epigenomic Annotation of Genetic Variants Using The Washington University Epigenome Browser.
10-1-2014. Rebecca's paper "Regulatory Network Decoded from Epigenomes of Surface Ectoderm-Derived Cell Types" has been accepted by Nature Communications. Congratulations Rebecca!
9-24-2014. Bo's paper "Comparative DNA methylome analysis of endometrial carcinoma reveals complex and distinct deregulation of cancer promoters and enhancers" has been accepted by BMC Genomics. Congratulations Bo!
9-17-2014. We now have our 3rd R01.
9-8-2014. Wash U EpiGenome Browser featured in Bio IT World.
8-22-2014. We now have our 2nd R01.
8-20-2014. Josh Jang joins the lab for a rotation. Welcome Josh!
8-18-2014. Renee joins the lab for her thesis study. Welcome back, Renee!
8-2-2014. 5th annual summer party. Some pictures.
7-28-2014. Nicole Rockweiler joins the lab for a rotation. Welcome Nicole!
7-1-2014. Xin has been promoted to faculty! He is now an Instructor. Congratulations Xin!
6-10-2014. Duc Ngo joins the lab as a summer student. Welcome Duc!
6-9-2014. Kenzie Foster joins the lab as a summer student. Welcome Kenzie!
5-30-2014. Methma Udawatta joins the lab as an Amgen Scholar. Welcome Methma!
5-21-2014. Michael Stevens successfully defended his PhD thesis "On the Analysis of DNA Methylation". Congratulations Dr. Stevens! Some pictures.
5-14-2014. Manishi Pandey joins the lab for a rotation. Welcome Manishi!
4-22-2014. We have received a 4-year Research Grant from the American Cancer Society.
4-18-2014. Vasavi's paper on TE driven evolution of transcription factor binding sites has been accepted by Genome Research. A reviewer said "it is a solid and valuable piece of work that has the potential to become a classic reference in the field of TE-mediated regulatory evolution". Congratulations Vasavi!!
4-7-2014. Xin's methylC Track paper is accepted by Bioinformatics. Congratulations Xin!
4-7-2014. GBM DNA methylation paper published at Genome Research: GBM DNA methylation.
3-13-2014. Vasavi Sundaram speaks at Keystone symposium about contribution of transposable elements to gene regulation. A picture.
2-5-2014. Our collaboration with Dr. Joe Costello's group at UCSF on Glioblastoma DNA methylation "Recurrent epimutations activate gene body promoters in primary glioblastoma" has been accepted by Genome Research! Bo is co-first author on this paper, and Daofeng and Vasavi are co-authors. Congratulations!!
12-5-2013. A model-based approach to systematically analyze the epigenomic functions in modulating transcription factor-DNA binding published at Plos Computational Biology: here.
12-2-2013. Renee Sears joins the lab for a rotation. Welcome Renee!
11-18-2013. Our TE DNA methylation paper is highlighted at NIH Commonfund front page: JUMPING GENES HAVE A JOB TO DO.
11-13-2013. UCSC Track Data Hub paper published at Bioinformatics: UCSC Track Data Hub.
11-1-2013. Jing Li joins the lab as an exchange student from Shanghai International Joint Cancer Institute, Second Military Medial University. Welcome Jing!
7-23-2013. mTAG-seq paper published at Nature Communications: mTAG-seq.
7-6-2013. Annual summer party. Some pictures.
6-27-2013. News and Views on our Nature Genetics paper: Hypomethylation marks enhancers within transposable elements.
6-18-2013. We now have our own R01.
6-13-2013. How often does one lab have TWO manuscripts accepted by Genome Research on the same day? It happened to our lab TODAY! Congratulations to Bo Zhang and Michael Stevens for beautiful work on M&M and methylCRF, and to all other co-authors!!
6-2-2013. Ronnie Fowle-Grider joins the lab for as a MSTP rotation student. Welcome Ronnie!
5-31-2013. Peter Edge joins the lab for the summer as a BioMedRAP student. Welcome Peter!
5-26-2013. TE DNA methylation paper is online at Nature Genetics: here.
5-2-2013. Mingchao's paper on TE DNA methylation has just been accepted by Nature Genetics! Congratulations to Mingchao, and to everyone who contributed hugely to the work that led to the paper's acceptance after Mingchao left the lab.
4-30-2013. Human Epigenome Browser paper in Nature Methods, again: here.
3-29-2013. Rebecca has won the very prestigious NSF fellowship! Congratulations Rebecca!!
3-20-2013. Xin's second Epigenome Browser paper is accepted by Nature Methods. Congratulations Xin!!
11-1-2012. Check out article in The Scientist features our Epigenome Browser: here.
11-1-2012. Spark paper in Genome Research: here.
6-21-2012. Rebecca has joined the lab for his thesis study! Welcome back, Rebecca!
6-9-2012. Mingchao's Farewell and Welcome Party at Wang's house. Some pictures.
6-8-2012. Comparative Epigenomics paper in Cell: here.
3-14-2012. Mingchao has been accepted by DBBS/MGG program! Congratulations Mingchao!
2-23-2012. Human Epigenome Browser in the news: here.
2-23-2012. Rebecca Lowdon joins the lab for rotation. Welcome, Rebecca!
2-1-2012. Our collaboration with Dr. Sheng Zhong's lab at UIUC on "Comparative epigenomic annotation of regulatory DNA" has just been accepted by Cell! In the work we introduced the concept of “comparative epigenomics” and suggested conserved co-localization of epigenomics marks can be used to discover regulatory elements. Our lab did the DNA methylation part of the project. Co-authors from our lab includes: Xiaoyun, Mingchao, and Ting.
1-23-2012. Madeline Keheler joins the lab for rotation. Welcome, Madeline!
12-1-2011. Human Epigenome Browser paper in Nature Methods: here.
11-10-2011. Taylor Southwick joins the lab for rotation. Welcome, Taylor!
9-9-2011. Xin's Epigenome Browser paper is accepted by Nature Methods. Congratulations Xin!!
8-30-2011. Zane Goodwin joins the lab for rotation. Welcome, Zane!
7-28-2011. Bo Zhang and Daofeng Li join the lab for their postdoc training. Welcome, Bo and Daofeng!!
7-16-2011. Summer Party at Wang's house. Some pictures.
7-15-2011. Hyung Joo has joined the lab for his thesis study! Welcome back, Hyung Joo!
6-13-2011. Ava Hughes joins the lab for her summer Young Scientist Program (YSP) fellowship. Welcome, Ava!
5-9-2011. Vasavi and Brett have joined the lab for their thesis studies! Welcome back, Vasavi and Brett!!
4-23-2011. Congratulations to Junchen for being elected President of I-CAN, a Wash U International graduate student association for Career development And Networking! 任重而道远, 不要辜负了大家的希望啊~~~
4-1-2011. Our study "Epigenetic Regulation as a Mechanism Underlying Host-Bacterial Relationships in the Gut" has been funded by the "Pilot and Feasibility Program" at Digestive Disease Research Core Center at Wash U (DDRCC). This injects ~$25k into Junchen's thesis work.
4-1-2011. Jessie wins a fellowship sponsored by NIDA R25 program to develop computational and statistical methods for analyzing human epigenomes. Congratulations, Jessie!
4-1-2011. Michael Stevens joins the lab from Computer Science department. Welcome, Michael!
2-7-2011. HyungJoo Lee joins the lab for rotation. Jessie Wang joins lab for her postdoc training. Welcome, HyungJoo and Jessie!
1-4-2011. Happy New Year! Ting has become "Basil O'Connor Scholar" of March of Dimes. This comes with a $150k grant over two years.
11-1-2010. Wash U Epigenome Visualization Hub (VizHub) is alive!
11-1-2010. One year birthday of the lab! We are welcoming Molly Gibson, Yuan Zhang and Ashley Quiggle for doing their rotations in the lab. We wish best luck to Brett Maricque and Vasavi Sundaram for their future rotations.
9-19-2010. Our DNA methylation comparison paper appears in Nature Biotechnology: here.
8-31-2010. Ruteja Barve joins the lab for rotation. Welcome, Ruteja!
8-21-2010. End of Summer Party at Wang's house. Some pictures.
8-20-2010. We win a one-year, $50k Developemental Research Award in Endometrial Cancer Research from Siteman Cancer Center and Endometrial Cancer SPORE. This award supports our collaboration with Dr. Paul Goodfellow on investigating the epigenomics of endometrial cancer.
8-1-2010. Mingchao Xie joins the lab as a research analyst. Sravya Tamma joins lab as a student intern and programmer. Welcome, Mingchao and Sravya!
7-29-2010. Our DNA methylation platform comparison paper is accepted by Nature Biotechnology. This is the result of a large consortium effort. Co-authors from our lab include Ting, Xin, Junchen and Kevin.
7-8-2010. Intragenic DNA methylation paper appears in Nature: here.
6-30-2010. Xin wins a fellowship sponsored by NIDA R25 program to develop computational tools for large genomics and epigenomics data integration and visualization. Congratualtions Xin! His tools will make contributions to the study of addiction. One way or another, we are all affected individuals...
6-30-2010. Vasavi Sundaram joins the lab for rotation. Welcome, Vasavi!
6-30-2010. Chris and Kevin finished their rotations and moved on to their thesis labs. Chris joins Barak Cohen's lab and Kevin joins Gautam Dantas's lab. Both of them are within 100 yards of our lab. We all enjoyed their time in the lab, and we wish them best of luck!
6-17-2010. Our application to investigate transposable element's role in cancer gene regulatory networks has been funded by Edward Mallinckrodt Jr. Foundation. This is our lab's first independent grant. We will receive three years of support totalling $180,000 in direct cost.
6-2-2010. Our joint grant application (with professor Joe Costello's lab at UCSF) to the Goldhirsh
Foundation has been funded! This is our first external grant, titled "Sequencing for Genetic
Mutations in Promoters via Integrative Epigenomics". We are going to identify both genetic and
epigenetic mutations in GBM (brain tumor). Junchen generated critical data (sequence coverage table)
during grant preparation.
Our joint application was one of the 153 Initial Proposal Applications and among the 19 Full Proposals selected for second stage review. The Goldhirsh Foundation has approved to make 1 two-year award and 3 one-year $200,000 awards. We are the only two-year $400,000 Award Recipient. The total direct cost for our lab is $80,000 for two years.
6-1-2010. David Russo joins the lab for summer study. Welcome, David!
6-1-2010. Brett Maricque joins the lab for rotation. Welcome, Brett!
6-1-2010. Michale Mahowald joins the lab for his postdoc training. Welcome Michael! Also a big congratulation to Michael for winning the W. M. Keck fellowship!
5-25-2010. Junchen Gu joins the lab for his thesis study. First graduate student of the Wang lab! Junchen is a McDonnell Scholar at McDonnell International Scholars Academy.
5-6-2010. Our 'break out' paper on intragenic DNA methylation is accepted by Nature. Co-authors from our lab are Chris, Xiaoyun and Ting. Maximiliaan Schillebeeckx from Rob Mitra's lab also contributed to this project and is a co-author. Congratulations! Nice beginning for the lab.
5-1-2010. Xin Zhou joins the lab as our first postdoc. Welcome Xin!
4-26-2010. Gaurav Singhal joins the lab for rotation. Welcome, Gaurav!
4-5-2010. Kevin Forsberg and Junchen Gu join lab for rotation. Welcome, Kevin and Junchen!
3-18-2010. Chris Fiore joins the lab as the first-ever rotation student. Welcome, Chris!
3-1-2010. Ting's review on visualizing genomes is published by Nature Methods.
1-18-2009 Xiaoyun Xing joins the lab. Welcome, Xiaoyun!
11-01-2009 Wang Lab officially launches.